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Before the arrival of Europeans, yellow fever was not a problem because indigenous people had built up an immunity. The disease was brought under control after the discovery that it is carried by the mosquito Aëdes aegypti. The first effective vaccines were produced by Max Theiler (18991972) of South Africa, for which he was awarded the 1951 Nobel Prize for Physiology or Medicine. The World Health Organization (WHO) estimates there are about 200,000 cases of yellow fever each year in Africa, with 30,000 deaths (2003).
The top left trigram symbolizes summer, south, and heaven. The top right trigram represents autumn, west, and the moon. The bottom right trigram stands for winter, north, and the Earth. The bottom left trigram represents spring, east, and the sun. Effective date: 21 February 1984.
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